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What special precautions should I follow?
tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft), and vitamins. If you have taken an MAO inhibitor [phenelzine (Nardil) or tranylcypromine (Parnate)] during the past 2 weeks, do not take sumatriptan. If you have taken another medication for migraine headaches such as dihydroergotamine (D.H.E. 45, Migranal), methysergide (Sansert), naratriptan (Amerge), rizatriptan (Maxalt, Maxalt-MLT), or zolmitriptan (Zomig) during the past 24 hours, do not tak e sumatriptan.

What side effects can this medication cause?
Less common or rare side effects may include:
- Abdominal discomfort, agitation, allergic reactions (severe), anxiety, asthma, backache, backflow of stomach contents, bleeding between periods, bl eeding in ears, nose or throat, breast tenderness, burning/numbness of tongue, changes in heart rhythm, chills, cold sensation, confusion, constipation, cough, depression, diarrhea, difficult or labor ed breathing, difficult or painful urination, difficulty concentrating, difficulty speaking, difficulty swallowing, drowsiness/calmness, dry mouth, ear infection, ear pain, exaggerated feeling of well -being, eye irritation, facial pain, fainting, fatigue, feeling strange, fever, general feeling of illness, headache, hearing loss, hearing disturbance,

How should this medicine be used?
Do not use .Imitrex for a headache that is different from your usual migraines . Instead, check with your doctor.

To relieve your migraine as soon as possible, use .Imitrex as soon as the hea dache pain begins. Even if you get warning signals of a coming migraine (an aura), you should wait until the headache pain starts before using .Imitrex. Using .Imitrex during the aura probably will no t prevent the headache from occurring. However, even if you do not use .Imitrex until your migraine has been present for several hours, the medicine will still work.

Lying down in a quiet, da rk room for a while after you use this medicine may help relieve your migraine.

What is this Drug
.Imitrex is used to treat severe migraine headaches. Many people find that their headaches go away completely after they take .Imitrex. Other people find that their headaches are much less painful, an d that they are able to go back to their normal activities even though their headaches are not completely gone. .Imitrex often relieves other symptoms that occur together with a migraine headache, suc h as nausea, vomiting, sensitivity to light, and sensitivity to sound.

.Imitrex is not an ordinary pain reliever. It will not relieve any kind of pain other than migraine headaches. This medi cine is usually used for people whose headaches are not relieved by acetaminophen, aspirin, or other pain relievers.

Symptoms of overdose may include:
Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

Symptoms of Imitrex overdose may include:
- Bluish tinge to the skin, convulsions, dilated pupils, inactivity, lack of coordination, paralysis, redness in the arms and legs, skin changes at the site of injection, slow breathing, sluggishness, tremor

Significant Interactions:
Do not take Imitrex ( Sumatriptan ) if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) within the last 14 days. T he combination could cause seizures, nausea, vomiting, sweating, flushing,


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